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Phalanx is Higgins Analytical’s latest addi-tion to a family of unique high perform-ance HPLC sorbents.The novel end cap-ping technology of this new sorbent is a continuation of the pioneering approach taken in 1996 when we introduced Targa ® , the first HPLC sorbent specifically designed for efficient LC-MS applications without TFA.

Based on an ultrapure,Type-B silica back-bone, Phalanx has a relatively high sur-face area of 430 m 2 /gm, but its very tight pore size distribution eliminates the undesirable side effects of micropores that often plague other high surface materials.

Optimum for Basic and Acidic com-pounds: Many modern HPLC sorbents employ embedded polar functionality. While these secondary structures can provide unique selectivity and eliminate undesirable solute/sorbent interaction, they often compromise the useful range of solutes or buffers that can be used. The figure on the left and those on page 2 illustrate that Phalanx columns pro-duce symmetrical peaks during the analy-sis of basic, neutral, and acidic com-pounds.

Wide pH operating range:The unique endcapping reduces acid/base hydrolysis of the bonded phase and greatly reduces silica solvation at high pH.

PHA L ANX

PHALANX Ultra High Density End Capping

Phases C18 article Sizes 3, 4.5, 10µm Pore Size 100Å Pore Volume 1.1mL/gm Surface Area 430m 2 /gm %Carbon (w/w) C18 = 18%

Phase type Monofunctional & fully endcapped Silica Class Type B

Applications

Phalanx is uniquely suitable for the efficient analysis of both acidic and basic analytes. In addition, its high capacity, good stability at high pH, and fast equilibration at extreme ranges of hydrophobicity make Phalanx a powerful option for challenging separation problems.

Phalanx HPLC columns and car tridges facilitate the development of robust assays for challenging analytes

Unique Features:

• Ideal for Basic and Acidic Analytes • Wide pH Range Stability • High Capacity

• No secondary Si-OH interaction • No metal contamination • Extreme hydrophobicity range

Standard Sizes:

• Special products for LC-MS • 0.075 - 20mm I.D. range

• Wide range of HPLC Car tridge and Column types • PEEK/titanium as well as stainless steel formats

High Selectivity

Wide range of solutes resolve quickly on a short HPLC column

Phalanx C18, 100x4.6mm, P/N: PS-1046-C185

(1) Uracil, (2) Caffeine, (3) Phenol, (4) n-Butylbenzene, (5) o-Terphenyl, (6) n-Amylbenzene, (7) Triphenylene 80% MeOH/water, 1mL/min

Guide to Phalanx Part Number

Px-xxxx-C185 Phalanx C18 5µm

See Page 23 for complete Part Number information