Page 21 - HAI_Price_List_2010

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Good Peak Symmetry for Basic

Compounds

The very low solute/sorbent interaction of Phalanx C18 is clearly illustrated by the analysis of basic compounds on a shor t 5cm cartridge column.

Phalanx C18, 50x2.1mm, P/N: PK-0521-C185

(1) Propanediol, (2) Diphenyldramine, (3) Acenapthene, (4) Amitiptyline.

65% MeOH/water 20mM KH2PO4 (pH 7.0), 200µL/min

Tricyclic Antidepressants

The very low solute/sorbent interaction of Phalanx C18 is clearly illustrated by the analysis of basic compounds on a 100x4.6mm HPLC column. Phalanx C18, 100x4.6mm, P/N: PS-1046-C185

(1) Desipramine, (2) Nor triptyline, (3) Acenaphthene,

(4) Imipramine, (5) Amitriptyline, (6) Trimipramine.

70% MeOH/water 20mM KH2PO4 (pH 7.0), 1.0mL/min

Unbuffered Pyridine Test for Free Silanol Activity

A very sensitive test for residual silanols produces a symmetrical pyridine peak in a low organic mobile phase without buffers.

Phalanx C18, 50x2.1mm, P/N: PK-0521-C185

(1) Uracil, (2) Phenol, (3) Pyridine 40% MeCN/water, 200µL/min

NIST Test Mix for Metal Activity and

Residual Silanols

Quininzarin, a strong metal chelator, and amitriptyline, a very sensitive solute for residual silanols, both elute with good recovery and symmetrical peaks on both Targa and Phalanx C18 columns. Targa® C18, 150x4.6mm, P/N:TS-1546-C185

Phalanx™ C18, 150x4.6mm, P/N: PS-1546-C185

(1) Uracil, (2) Toluene, (3) Ethylbenzene, (4) Quinizarin, (5) Amitiptyline.

80% MeOH/buffer, 1.5mL/min

Nucleosides

Like its cousin Targa, Phalanx’s unique end-capping chemistry works equally well at extreme hydrophilic and hydrophobic ranges. Phalanx C18, 50x2.1mm, P/N: PK-0521-C185

(1) Cytosine, (2) Uracil, (3) Cytidine, (4) Uridine, (5) Thymine. 100%Water, 1.0mL/min

TAR

PHA

3

3

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PHA L ANX A P P L I C AT I ONS

See page 28 for an interesting comparison of PHALANX to KROMASIL C18 for an analysis of a pharmaceutical drug.